Comparing Ayala Pharmaceuticals (NASDAQ:AYLA) & Compugen (NASDAQ:CGEN)

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Ayala Pharmaceuticals (NASDAQ:AYLA) and Compugen (NASDAQ:CGEN) are both small-cap medical companies, but which is the superior business? We will contrast the two businesses based on the strength of their dividends, earnings, analyst recommendations, institutional ownership, risk, profitability and valuation.


This table compares Ayala Pharmaceuticals and Compugen’s net margins, return on equity and return on assets.

Net Margins Return on Equity Return on Assets
Ayala Pharmaceuticals N/A N/A N/A
Compugen N/A -32.53% -27.13%

Analyst Recommendations

This is a summary of recent ratings and price targets for Ayala Pharmaceuticals and Compugen, as reported by MarketBeat.

Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Ayala Pharmaceuticals 0 1 3 0 2.75
Compugen 0 0 8 0 3.00

Ayala Pharmaceuticals presently has a consensus price target of $24.00, indicating a potential upside of 101.68%. Compugen has a consensus price target of $19.75, indicating a potential upside of 30.06%. Given Ayala Pharmaceuticals’ higher possible upside, equities analysts plainly believe Ayala Pharmaceuticals is more favorable than Compugen.

Earnings & Valuation

This table compares Ayala Pharmaceuticals and Compugen’s revenue, earnings per share and valuation.

Gross Revenue Price/Sales Ratio Net Income Earnings Per Share Price/Earnings Ratio
Ayala Pharmaceuticals $2.33 million 65.27 -$17.79 million N/A N/A
Compugen $17.80 million 58.37 -$27.34 million ($0.43) -35.31

Ayala Pharmaceuticals has higher earnings, but lower revenue than Compugen.

Institutional & Insider Ownership

20.3% of Ayala Pharmaceuticals shares are owned by institutional investors. Comparatively, 57.4% of Compugen shares are owned by institutional investors. 9.5% of Compugen shares are owned by insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a stock will outperform the market over the long term.

About Ayala Pharmaceuticals

Ayala Pharmaceuticals, Inc., a clinical-stage biopharmaceutical company, focuses on developing and commercializing small molecule therapeutics for patients suffering from rare and aggressive cancers. The company's lead product candidate is AL101, which is an intravenous injectable small molecule gamma secretase inhibitor (GSI) that is in Phase II clinical trial for the treatment of recurrent/metastatic adenoid cystic carcinoma for patients bearing Notch-activating mutations. It is also involved in developing AL102, an oral injectable small molecule GSI that is in Phase I clinical trial for the treatment of desmoid tumors. Ayala Pharmaceuticals, Inc. has a collaboration agreement with Novartis International Pharmaceutical Limited to develop AL102 for the treatment of multiple myeloma. The company was founded in 2017 and is based in Rehovot, Israel.

About Compugen

Compugen Ltd., a therapeutic discovery company, engages in the research, development, and commercialization of therapeutic and product candidates in Israel and Europe. The company's therapeutic pipeline consists of immuno-oncology programs against novel drug targets in the areas of unmet medical needs in various cancer types and patient populations. Its product pipeline consists of COM701, a monoclonal antibody designed to block the interaction of PVRIG with its cognate ligand, PVRL2; CGEN-15001T, an immuno-oncology therapeutic program for ILDR2; and COM902, a therapeutic antibody candidate for its TIGIT program. The company's pipeline also comprises therapeutic proteins include CGEN-15001, a fusion protein drug candidate for autoimmune diseases, including extracellular domain of ILDR2 and an IgG Fc domain. Compugen Ltd. has a clinical trial collaboration with Bristol-Myers Squibb Company to evaluate the safety of COM701 in combination with Bristol-Myers Squibb's programmed death-1 immune checkpoint inhibitor Opdivo in patients with advanced solid tumors. The company was incorporated in 1993 and is headquartered in Holon, Israel.

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